Macroplastique® is an injectable soft-tissue bulking agent for treating stress urinary incontinence primarily due to intrinsic sphincter deficiency, and vesicoureteral reflux. Macroplastique® is made up of two parts – the water-soluble gel (polyvinylpyrrolidone) that is absorbed and removed from the body in urine and the man-made, rubber-like, silicone elastomer implant material (cross-linked polydimethylsiloxane) that stays in place permanently and is not absorbed by the body. It is this permanent material that causes the bulking effect around the urethra after implantation.
